Greene to be Published in Journal of Neuroscience

The Magnet class of 2015 is intent on squeezing every last bit of potential out of their senior year.  We learned just today that Magnet senior Rachel Greene, who worked in an internship this year at the Oregon Health & Science University (OHSU), will receive a co-author credit in the July, 2015 issue of The Journal of Neuroscience for her work exploring the effects of exercise as treatment in a mouse model of Parkinson’s Disease.

According to Ms. Greene, “Parkinson’s disease (PD) is a neurodegenetive disorder caused by a dopamine deficiency in the substantia nigra that affects an estimated four to six million worldwide. The most prevalent symptoms of PD include tremors, rigidity, freezing of gait, and some mental health issues such as depression. Since there is no cure for PD, researchers are continually looking for possible methods to stop the progression of the disease. My experiment is focused on exercise as one such method. Using a mouse model of PD, I analyzed a number of PD and exercise-related proteins, namely tyrosine hydroxylase, in the brain using western blotting and immunohistochemistry procedures. However, I did not find data suggesting that exercise is an effective method to alter the progression of the disease.” You can read the first page of the soon-to-be-published article here:  Intervention with Exercise

Greene joins three other Class of 2015 MST Magnet students who, based on their internship work, have been published in major journals this year.  She plans on attending Northwestern next fall and studying biological sciences with an emphasis on neurobiology.

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