2013 Magnet Alumna Published in Journal of Neuroscience

Recent CHS/Magnet grad Eden Pollock helped design a study whose results were recently published in The Journal of Neuroscience: Presynaptic Alpha-Synuclein Aggregation in a Mouse Model of Parkinson’s Disease.  Pollock attends University of Washington.  Congratulations, Eden!  “Parkinson’s disease and dementia with Lewy bodies are associated with abnormal neuronal aggregation of α-synuclein. However, the mechanisms of aggregation and their relationship to disease are poorly understood. We developed an in vivo multiphoton imaging paradigm to study α-synuclein aggregation in mouse cortex with subcellular resolution. We used a green fluorescent protein-tagged human α-synuclein mouse line that has moderate overexpression levels mimicking human disease …”edenjnspublish

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